Abstract: Jewelry industry is currently still a traditional manufacturing industry, and its development has encountered a bottleneck. Mass personalization, which has been successfully practiced in many industries, is a trend in the transformation of the traditional manufacturing industries. However, the design and production process of it is complicated, which needs to be adjusted according to the characteristics of the industry.Therefore, according to the characteristics of jewelry industry, this paper combines the concept of mass personalization, and proposes the mass personalization system solution for jewelry industry based on customer to business. It focuses on the analysis of the important parts in this design model, and advances the practical application of this model in the jewelry industry through the discussion of personalized demand elements, modular design, customer-driven design, and the key technologies of personalized design. It also discusses the mass personalization design in jewelry industry, and further illustrates that this model is a suitable design and production mode for jewelry with strong personalized demands of customers, which has certain reference value for the practical application of this model in jewelry industry.